Flomax
For more information check out: Flomax today!
Q: Would Flomax be a good Secret Santa gift for the guy in the office?
That already sounds like a over pressurized fire-hose at the urinal? When this guy wizzes, people take cover behind stall walls and run for cover. I was hoping the Flomax would be enough to splash it back on himself.
This Question will die in POLL: 10 answers >OR< 5 answers >OR< 75 answers and no stars?
Gotta love the odds of the last choice.
A: If he is one of those ‘go with the flow’ guys, HECK YES! Great idea….LOL!
Q: Why is there a warning for not eating grapefruit with Flomax?
I use Flomax and wonder why I can’t eat grapefruit. Does anyone know?
A: Grapefruit affects enzymes in your intestines which can lead to greater absorbtion of certain medications which could possibly bring them to toxic levels in your bloodstream.
Tamsulosin (Flomax) has the possiblilty of this type of interaction so grapefruit should be avoided.
Karma.
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Q: Is there another treatment for benign prostatic hyperplasia (BPH) besides Doxazosin and Flomax?
I suffer with an enlarged prostate and the two medicines that I take now (Flomax and Doxazosin) causes my tongue to swell. Is there another medication I can take that doesn’t cause my tongue to swell. Help me please!
A: There are multiple medications out there for this and the fact that you are having tongue swelling IS an allergic reaction and the medications should be stopped immediately. Uroxatral and terazosin are alternatives.
Your doctor may decide to go another way and try something like Avodart or Proscar (generic is finasteride) to actually help shrink the size of the prostate. These take longer to get the full effect – say six months or more – but our practice uses them with relatively good results.
Q: How much alcohol can you have with Avodart and/or Flomax?
Just a ballpark estimate would work. My father, who is on the meds, is contemplating buying a 30-pack of beer and wants to know if he can have any of it.
A: I woulnt have any but if he realy wants some I would talk to a pharmacist
Q: I have been taking Flomax for several days to help get rid of Kidney stones and suffered a side effect?
When I ejaculate, there was almost nothing there and they said this is a side effect. If I stop taking the Flomax Will everything go back to normal? and how long would that take? Thanks all
A: been there. I would talk to the doctor. depending on the kidney stones, or bladder stones and there composition, there are different meds that are available. I do not know how accute your stones were, but I know that a blank every now and again is alot better than passing a boulder through a pecker. that was my outlook. just a passing idea, have your DR. check for uric acid levels next time you are in, if they are high, you may be open to getting GOUT as well, there is meds and diet to help eith this as well. good luck
Q: Is Flomax basically a safe medicine?
I’ve read all kinds of scary things about Flomax on the internet – from constant erections to retrograde ejaculation. Are these side effects common or are they minimal in terms of the number of occurrences in people that use it? I would very much appreciate some perspective on this matter.
A: My husband uses this and it is relatively safe and works. As you know drug interactions vary from individual to individual.
Q: What is diference between FloMax and Advodart?
I am 56 and have been having trouble with irregular stream. which is better for me? NO INS.
A: flomax
Side effects
What are the most common side effects associated with FLOMAX?
Important Safety Information
FLOMAX is approved to treat male urinary symptoms due to BPH. Only your doctor can tell if your symptoms are due to BPH and not another condition such as prostate cancer. Common side effects of FLOMAX are runny nose, dizziness and decrease in semen. A sudden decrease in blood pressure may occur upon standing, rarely resulting in fainting. So when starting FLOMAX, avoid situations where injury could result. If considering cataract surgery, tell your eye surgeon you have taken FLOMAX capsules.
Can I take FLOMAX while I’m using other medications?
FLOMAX can be taken with these common antihypertensive (high blood pressure) and cardiovascular (heart disease) medications without dosage adjustment:
atenolol
enalapril
nifedipine
However, there are some medications that should be used with caution when taking FLOMAX, such as:
warfarin (a blood-thinning medication also known as Coumadin®)
cimetidine (a medication that treats ulcers)
Always tell your doctor what prescription and over-the-counter drugs, vitamins and/or dietary supplements you are taking. This is important so that your doctor can avoid prescribing medications that may negatively interact with each other.
avodart
SIDE EFFECTS
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trial of another drug and may not reflect the rates observed in practice. The adverse reaction information from clinical trials does, however, provide a basis for identifying the adverse events that appear to be related to drug use and for approximating rates.
Most adverse reactions were mild or moderate and generally resolved while on treatment in both the AVODART and placebo groups. The most common adverse events leading to withdrawal in both treatment groups were associated with the reproductive system.
Over 4,300 male subjects with BPH were randomly assigned to receive placebo or 0.5-mg daily doses of AVODART in 3 identical 2-year, placebo-controlled, double-blind, Phase 3 treatment studies, each with 2-year open-label extensions. During the double-blind treatment period, 2,167 male subjects were exposed to AVODART, including 1,772 exposed for 1 year and 1,510 exposed for 2 years. When including the open-label extensions, 1,009 male subjects were exposed to AVODART for 3 years and 812 were exposed for 4 years. The population was aged 47 to 94 years (mean age, 66 years) and greater than 90% Caucasian. Over the 2-year double-blind treatment period, 376 subjects (9% of each treatment group) were withdrawn from the studies due to adverse experiences, most commonly associated with the reproductive system, with similar findings during the 2-year open-label extensions. Withdrawals due to adverse events considered by the investigator to have a reasonable possibility of being caused by the study medication occurred in 4% of the subjects receiving AVODART and in 3% of the subjects receiving placebo. Table 1 summarizes clinical adverse reactions that were reported by the investigator as drug-related in at least 1% of subjects receiving AVODART and at a higher incidence than subjects receiving placebo.
Table 1. Drug-Related Adverse Events* Reported in ≥1% Subjects Over a 24-Month Period and More Frequently in the Dutasteride Group Than the Placebo Group (Pivotal Studies Pooled)
Adverse Event Onset
Adverse Events Month 0-6 Month 7-12 Month 13-18 Month 19-24
Dutasteride (n) (n = 2,167) (n = 1,901) (n = 1,725) (n = 1,605)
Placebo (n) (n = 2,158) (n = 1,922) (n = 1,714) (n = 1,555)
Impotence
Dutasteride 4.7% 1.4% 1.0% 0.8%
Placebo 1.7% 1.5% 0.5% 0.9%
Decreased libido
Dutasteride 3.0% 0.7% 0.3% 0.3%
Placebo 1.4% 0.6% 0.2% 0.1%
Ejaculation disorder
Dutasteride 1.4% 0.5% 0.5% 0.1%
Placebo 0.5% 0.3% 0.1% 0.0%
Gynecomastia†
Dutasteride 0.5% 0.8% 1.1% 0.6%
Placebo 0.2% 0.3% 0.3% 0.1%
*A drug-related adverse event is one considered by the investigator to have a reasonable possibility of being caused by the study medication. In assessing causality, investigators were asked to select from 1 of 2 options: reasonably related to study medication or unrelated to study medication.
† Includes breast tenderness and breast enlargement.
Long-Term Treatment (Up to 4 Years)
There is no evidence of increased drug-related sexual adverse events (impotence, decreased libido and ejaculation disorder) or gynecomastia with increased duration of treatment. The relationship between long-term use of dutasteride and male breast neoplasia is currently unknown.
Postmarketing Experience
The following adverse reactions have been identified during postapproval use of AVODART. Because these reactions are reported voluntarily from a population of uncertain size, it is not possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Decisions to include these reactions in labeling are based on one or more of the following factors: (1) seriousness of the reaction, (2) frequency of reporting, or (3) potential causal connection to AVODART.
· allergic reactions, including rash, pruritus, urticaria, and localized edema.
DRUG INTERACTIONS
Care should be taken when administering dutasteride to patients taking potent, chronic CYP3A4 inhibitors (see PRECAUTIONS: Use with Potent CYP3A4 Inhibitors).
Dutasteride does not inhibit the in vitro metabolism of model substrates for the major human cyto-chrome P450 isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) at a concentration of 1,000 ng/mL, 25 times greater than steady-state serum concentrations in humans. In vitro studies demonstrate that dutasteride does not displace warfarin, diazepam, or phenytoin from plasma protein binding sites, nor do these model compounds displace dutasteride.
Digoxin: In a study of 20healthy volunteers, AVODART did not alter the steady-state pharmacokinetics of digoxin when administered concomitantly at a dose of 0.5 mg/day for 3 weeks.
Warfarin: In a study of 23 healthy volunteers, 3 weeks of treatment with AVODART 0.5 mg/day did not alter the steady-state pharmacokinetics of the S- or R-warfarin isomers or alter the effect of warfarin on prothrombin time when administered with warfarin.
Alpha-Adrenergic Blocking Agents: In a single sequence, crossover study in healthy volunteers, the administration of tamsulosin or terazosin in combination with AVODART had no effect on the steady-state pharmacokinetics of either alpha-adrenergic blocker. The percent change in DHT concentrations was similar for AVODART alone compared with the combination treatment.
A clinical trial was conducted in which dutasteride and tamsulosin were administered concomitantly for 24 weeks followed by 12 weeks of treatment with either the dutasteride and tamsulosin combination or dutasteride monotherapy. Results from the second phase of the trial revealed no excess of serious adverse events or discontinuations due to adverse events in the combination group compared to the dutasteride monotherapy group.
Calcium Channel Antagonists: In a population pharmacokinetics analysis, a decrease in clearance of dutasteride was noted when co-administered with the CYP3A4 inhibitors verapamil (-37%, n = 6) and diltiazem (-44%, n = 5). In contrast, no decrease in clearance was seen when amlodipine, another calcium channel antagonist that is not a CYP3A4 inhibitor, was co-administered with dutasteride (+7%, n = 4).
The decrease in clearance and subsequent increase in exposure to dutasteride in the presence of ver-apamil and diltiazem is not considered to be clinically significant. No dose adjustment is recommended.
Cholestyramine: Administration of a single 5-mg dose of AVODART followed 1 hour later by 12 g cholestyramine did not affect the relative bioavailability of dutasteride in 12 normal volunteers.
Other Concomitant Therapy: Although specific interaction studies were not performed with other compounds, approximately 90% of the subjects in the 3 Phase III pivotal efficacy studies receiving AVODART were taking other medications concomitantly. No clinically significant adverse interactions could be attributed to the combination of AVODART and concurrent therapy when AVODART was co-administered with anti-hyperlipidemics, angiotensin-converting enzyme (ACE) inhibitors, beta-adrenergic blocking agents, calcium channel blockers, corticosteroids, diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), phosphodiesterase Type V inhibitors, and quinolone antibiotics.
Drug/Laboratory Test Interactions
Effects on Prostate-Specific Antigen: PSA levels generally decrease in patients treated with AVODART as the prostate volume decreases. In approximately one-half of the subjects, a 20% decrease in PSA is seen within the first month of therapy. After 6 months of therapy, PSA levels stabilize to a new baseline that is approximately 50% of the pre-treatment value. Results of subjects treated with AVODART for up to 2 years indicate this 50% reduction in PSA is maintained. Therefore, a new baseline PSA concentration should be established after 3 to 6months of treatment with AVODART (see PRECAUTIONS: Effects on PSA and Prostate Cancer Detection).
Hormone Levels: In healthy volunteers, 52 weeks of treatment with dutasteride 0.5 mg/day (n = 26) resulted in no clinically significant change compared with placebo (n = 23) in sex hormone binding globulin, estradiol, luteinizing hormone, follicle-stimulating hormone, thyroxine (free T4), and dehydro-epiandrosterone. Statistically significant, baseline-adjusted mean increases compared with placebo were observed for total testosterone at 8weeks (97.1 ng/dL, p<0.003) and thyroid-stimulating hormone (TSH) at 52weeks (0.4 mcIU/mL, p<0.05). T
Q: Flomax. Has anyone had any extreme dizzy spells from taking the prescription drug Flomax?
My brother said that he took Flomax for 6 months and got so dizzy, that one time, he had to go down to his knees until it subsided. I’m on Flomax now and would like to hear from anyone taking the drug now. Thanks.
A: Yes, it could be a side effect of Flomax which can cause dizziness. Anyway see a doctor but the site below is good as it sets it out nice and clear.
Q: Is there a natural herb or medicine instead of taking FLOMAX for urinary problems??
They are SO EXPENSIVE,,$60 copay with my ins. co. Canada already has the generic and SO MUCH cheaper. I wish I knew a way to find out when it’s going generic in the states.
A: Natural treatments for prostate problems have been very helpful in relieving the symptoms, and reducing the enlargement.
1.The first line of defense is to maintain low cholesterol levels by avoiding a high-fat diet. It seems that the amount of fat, particularly saturated fat, in the diet affects hormone levels, which in turn cause prostate problems. Of course many men are watching their cholesterol levels these days; this is all to the good in controlling an enlarged prostate.
2.The mineral zinc is the backbone of treatment for men with prostate problems. Men with BPH have low levels of zinc in prostatic fluids, and supplementation can raise these levels and reduce the enlargement.
3.Essential fatty acids are also helpful in relieving an enlarged prostate. Researchers postulate that essential fatty acids work by influencing prostaglandin production; prostaglandin deficiency may be a cause of BPH. The best common sources of essential fatty acids are flaxseed oil, sunflower oil, and soy oil.
4.There is a botanical that has given patients relief and many studies have found it clinically effective for relieving BPH. It’s called Serenod repem or, more commonly, saw palmetto. Taken in extract form, it relieves prostate irritation.
5.It’s important to limit the amount of alcohol you consume, particularly beer. One of the hormones that contribute to prostate problems is increased by the consumption of beer and other alcoholic drinks.
6.Sometimes there is a connection between hidden food sensitivities and prostate problems. If the prostate doesn’t seem to be inflamed, frequent urination could be caused by a food. If you find that you have frequent urination on some nights but on other nights you’re not having a problem, it could be that something you’re eating is the cause (in many cases, spicy foods are the culprits). You have to pay attention to what you eat the day or night before you experience frequent urination.
7.Many men rush to relieve themselves, only partly emptying their bladder and never fully relaxing the muscles in the pelvic floor. To help prevent BPH and to relieve its progression, it’s important to void whenever you feel the urge; if at all possible, don’t hold it. In addition and most important, you should fully relax the muscles in the pelvic floor when voiding and keep them relaxed until the bladder is empty.
8.Take the following supplement
Flaxseed oil: one to two teaspoons per day for several months. In addition, add sunflower oil or soy oil to your diet.
Vitamin E: 400 IU daily.
Zinc: 60 mg daily.
Saw palmetto160 mg. Twice daily. You can find it in health food stores.
Reminder : Talk to your doctor before taking supplements.
Q: What effect does flomax have on operation for cataracts?
A: usually a pretty good effect
Q: Is there a drug like Flomax available for dogs when they can’t always control their urination?
A: Yes. Actually there are several, but you must first have your dog tested to make sure that it is incontinence and not an infection for some other underlying problem. Most incontinence problems occur with spayed females. Proin, PPA, and DES are three meds. I would make an appt. with your vet to discuss the options.
Q: What’s a good online site to buy Flomax?
My dad’s insurance doesn’t cover full cost, so he pays retail. He’s 75 and on a very fixed budget. Suggestions?
A: you can order a generic online at The-med-store.com which is the site I use when buying a prescription locally is just too expensive.
Q: Are there any alternatives to Flomax or AVODART that really work??
First I hear this is good then that is good,,WHAT IS GOOD NATURALLY.
A: I have heard saupamento excuse the spelling
Q: Does FLOMAX for unirary problems make you tired?
My doc has me on BACTRIM antibiotic for urinary inf AND Flowmax. It seems to make me tired. I’m also on BP med. Should I take both??
A: As far as taking all of those medications together, please consult your pharmicist.
One of the possible side effects of Flomax is sleepiness. For other side effects of this medication and more information please see this site:
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a698012.html
Q: I have an enlarged prostate i want to know which med is better Flomax or Avodart any opinios?
A: ask a doctor and see what he recommends
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